The Zinc Finger Transcription Factor Ovol2 Acts Downstream of the Bone Morphogenetic Protein Pathway to Regulate the Cell Fate Decision between Neuroectoderm and

This study uncovers the mechanism of how BMP signaling regulates early cell fate decision.During early embryonic development, bone morphogeneticprotein (BMP) signaling is essential for neural/non-neural cellfate decisions. BMP signaling inhibits precocious neural differ-entiation and allows for proper differentiation of mesoderm,endoderm, and epidermis. However, the mechanisms underly-ingtheBMPpathway-mediatedcellfatedecisionremainlargelyunknown. Here, we show that the expression of