Primary Sinonasal Mucosal Melanoma with Unusual Long-Term Survival

The primary sinonasal mucosal melanoma is a rare entity. It has a grave clinical course with a dismal prognosis. A patient with long- term survival is very unusual. We report a 70-year-old male with a primary sinus mucosal melanoma and multiple metachronous disseminations. The patient underwent curative surgery for the primary sinus lesion and multiple salvage therapies for distant failures. A survival period of more than 10 years was achieved. We establish the value of repeated salvage therapies in prolonging survival time for this patient with a primary sinonasal mucosal melanoma.