Surgical treatment of areolar neurofibromas
2012
Neurofibromatosis type 1 (NF1) is an autosomal dominant condition with well-recognized clinical signs [1]. Skin lesions, benign tumors of peripheral nerves, and sometimes tumors of the central nervous system characterize neurofibromatosis clinically [2]. These tumors were first described by Smith in 1849 and later by Von Recklinghausen in 1882 [3]. Hence, NF is also known as Von Recklinghausen’s disease. It has an incidence of approximately 1 in 3,000 live births [4]. In 1988, the National Health Service established the criteria for the diagnosis of NF1 [5]. For a diagnosis to be made, at least two of the following seven signs must be present. These include:
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