Multidrug-resistant CTX-M-15-positive Klebsiella pneumoniae ST307 producing urinary tract infection in a dog in Brazil.

Abstract Background Klebsiella pneumoniae sequence type ST307 has emerged as a new high-risk clone worldwide. Objective To report the draft genome sequence of a multidrug-resistant CTX-M-15-positive K. pneumoniae strain producing urinary tract infection in a companion animal. Methods The whole genome was sequenced on an Illumina NextSeq platform and de novo assembled using SPAdes. Data analysis was performed using online tools from the center for genomic epidemiology. Results The genome size was calculated at 5,450,575 bp, containing a total of 5,355 protein-coding sequences. The strain was assigned to the high-risk sequence type ST307 and carried the clinically relevant blaCTX-M-15 gene, besides other genes conferring resistance to aminoglycosides, tetracyclines, quinolones, trimethoprim, and fosfomycin. Conclusion These data offer novel information for comparative genomic analyses, in order to track transmission dynamics and the epidemiology of the newly emerging high-risk clone ST307.