Abstract 16106: Impact of Visit-to-Visit Systolic Blood Pressure Variability on Coronary Artery Atherosclerosis in Hypertensive Patients Without Known Coronary Artery Disiease

Introduction: Visit-to-visit variability in systolic blood pressure (SBP) has been reported as a risk of long-term cardiovascular events in hypertensive patients. However, a little has been known that the effect of visit-to-visit SBP variability in the presence of the severity and extent of coronary artery disease (CAD). Hypothesis: Visit-to-visit SBP variability, as well as mean SBP, may be associated with the severity and extent of coronary artery atherosclerosis in hypertensive patients. Methods: We analyzed consecutive 697 hypertensive patients who underwent computed tomography coronary angiography (CTCA) for the evaluation of CAD. Visit-to-visit variability in SBP was measured by the coefficient of variation (CV) of SBP (CVSBP) obtained at 6-clinic visits before CTCA. CTCA stenosis severity was categolized as no CAD, non-obstructive CAD (less than 50% diameter stenosis), and obstructive CAD (more than 50% diameter stenosis). The extent of CAD was categolized as non-extensive (less than 4 segments) or...