Arnav: Site specific error models to identify variants in RNA

Summary: We present Arnav (Analysis of RNA variants) a lightweight and easy-to-use statistical method for detecting mutations from RNA sequencing data. Site-specific error models allow Arnav to call variants with high specificity when the true variant allele fraction is unknown. We show the utility of Arnav by identifying variants using RNA sequencing data from the GTEx project. Availability and Implementation: Arnav is implemented in C++ and is distributed under the GPL license at https://github.com/gatoravi/arnav Contact: aramu@wustl.edu