Glycolipid-Mediated Basophil Activation in Alpha-Gal Allergy

Onyinye I. Iweala,Shailesh Choudhary,Claire T. Addison,Cole J. Batty,Camille M. Kapita,Claire Amelio,Alexander J. Schuyler,Shenglou Deng,Eric M. Bachelder,Kristy M. Ainslie,Paul B. Savage,Patrick J. Brennan,Scott P. Commins

Glycolipid-Mediated Basophil Activation in Alpha-Gal Allergy

2020

Onyinye I. Iweala
Shailesh Choudhary
Claire T. Addison
Cole J. Batty
Camille M. Kapita
Claire Amelio
Alexander J. Schuyler
Shenglou Deng
Eric M. Bachelder
Kristy M. Ainslie
Paul B. Savage
Patrick J. Brennan
Scott P. Commins

: Alpha-gal-containing glycolipids activate basophils sensitized with plasma from alpha-gal allergic subjects in an IgE-dependent manner suggesting a role for glycolipid in the effector phase of IgE-mediated food allergy.

Keywords:

Basophil
Immunology
Food allergy
Glycolipid
Medicine
Alpha-gal allergy
Basophil activation
Effector

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