Hepatosplenic T-cell lymphoma: A clinical diagnostic challenge
2020
Hepatosplenic T-cell lymphoma (HSTCL) is a rare variant of T-cell lymphoma and comprises less than 5% of all peripheral T-cell lymphomas. These lymphomas have an aggressive course and dismal prognosis. We report a case of a 28-year-old male who presented with repeated episodes of fever and abdominal pain. Ultrasonography revealed hepatosplenomegaly. Liver biopsy performed showed sinusoidal lymphoid cell infiltration of the T-cell immunophenotype with aberrant antigen loss. The case was finally diagnosed as HSTCL.
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