Longitudinal three-dimensional visualisation of autoimmune diabetes by functional optical coherence imaging.
2016
Aims/hypothesis
It is generally accepted that structural and functional quantitative imaging of individual islets would be beneficial to elucidate the pathogenesis of type 1 diabetes. We here introduce functional optical coherence imaging (FOCI) for fast, label-free monitoring of beta cell destruction and associated alterations of islet vascularisation.
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