Central obesity and asthma outcomes in adults diagnosed with asthma.

Objective. The potential role of central obesity in asthma outcomes has been examined in a few studies. The aim of this study was to examine the relationship between central obesity and asthma outcomes in a group of Iranian asthma patients. Methods. One hundred and forty-two outpatients with asthma were studied. Central obesity was defined according to National Institute of Health (NIH) and Asian waist circumference (WC) and waist-to-hip ratio (WHR) cut-offs. Asthma outcomes including asthma control, pulmonary function, and morbidity were evaluated. The association between central obesity and asthma outcomes was studied by linear and logistic regression analyses. Results. Linear regression analysis showed a significant association of WHR-based central obesity with forced expiratory volume in 1 s (FEV1) (β = −9.04; p-value = .044) and forced vital capacity (FVC) (β = −10.52; p-value = .012). Logistic regression analysis showed a significant increased risk of asthma attacks in 3 months with Asian WC-based c...