Extra-deep guide-catheter intubation for direct thromboaspiration

In response to the letter by Dr. Deora and colleagues [1], we appreciate their interest in our work [2] and we are pleased that our report has triggered new ideas and challenges in the interventional cardiology field. Upon the comments raised by our colleagues [1] and in order to clarify any potential misconceptions, we believe it is worthy to further highlight some statements that have been clearly stated in our manuscript [2]: