Hepatic artery infusion in surgical therapy of hepatic metastases from colorectal cancer

15077 Background: The gold standard in the treatment of liver metastases from colorectal cancer (CRC) is surgical resection. Unfortunately most of the patients are unresectable. The purpose of the study was to assess the role of hepatic arterial infusion in the management of these patients. Methods: Our clinical series included 274 patients with liver metastases from CRC (period 1978–2001). One hundred thirty four pts were treated surgically as follows: resection (87 pts), hepatic artery infusion (HAI) (30 pts), resection plus HAI (13 pts), and ablation plus HAI (8 pts). The remaining 139 pts received systemic therapy treatment. A separate (historic) group had supportive care only (historic) group had supportive care only (historic control). Overall and median survival was measured by Kaplan-Meier method from treatment of liver metastases in the surgical group and from diagnosis in systemic therapy/historic groups. Conclusion: A multi-option strategy is essential in surgical planning for management of liv...