Bacillus marinus S-1 and anti-tumor active polypeptide produced thereby
2013
The invention relates to a bacillus marinus S-1 and an anti-tumor active polypeptide produced thereby. The bacillus marinus S-1 is cultivated, separated and screened from sea mud in the south china sea, so as to obtain a marine microbial bacteria strain of marine bacillus genus (Bacillus sp.) for producing the anti-tumor active polypeptide. The strain S-1 is aerobic bacteria, has good salt tolerance, and grows well in 7 w/v% of NaCl culture solution, wherein the growth pH range is 5.0-9.0; the growth temperature range is wide; the bacillus marinus S-1 can well grow in the environment of 15-37 DEG C; a gene sequence of 16S rDNA of the strain S-1 is shown in a figure. The polypeptide produced by the bacillus marinus S-1 has anti-tumor activity, and is expected to be an anti-tumor drug for treating a liver cancer.
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