Künstlicher Aszites mit oder ohne Cortison-Zusatz im Rahmen medikamentöser Therapieansätze zur Adhäsionsprophylaxe in der operativen Gynäkologie

Postoperative adhesions are extremely important in gynaecology, especially since in up to 20% of cases, infertility is secondary to pelvic adhesions. Various adjuvants have been proposed for the prevention of adhesions, with agents for the inhibition of the physiologic inflammatory reactions paying a central role. The aim of the present study was to assess the antiadhesive effect of artificial ascites with and without cortisone. Artificial ascites with physiological NaCI solution with or without hydrocortisone was created, in 20 patients each undergoing an operative laparoscopic procedure for treatment of endometriosis of the tubo-ovarian functional unit. Evaluation at second-look laparoscopy (12-24 weeks after the initial operation) showed no significant differences between the 2 groups. It can be concluded that cortisone is of no additional benefit for the prevention of adhesions.