Correlation of the pathogenesis of male primary varicose vein of lower extremity and varicocele

Varicose vein of lower extremity and varicocele show tortuosity,dilatation in different parts of venous.They are linked in venous anatomy structure.Their pathogenesis are not clear,but have certain similarity in venous wall structures,venous pressure,venous valvular incompetence,venous insufficiency,level of serum sex homone and apoptosis.We review the related literature to investigate the correlation between pathogenesis of them,in order to provide reference for the etiology,diagnosis and treatment. Key words: Lower extremity ;  Varicose veins ;  Varicocele ;  Pathogenesis