Abstract 18630: Targeting Inhibitor of Protein Phosphatase 2A (I2PP2A) Mediates Plasma Membrane Beta-Adrenergic Receptor Resensitization
2013
βAR downregulation and desensitization are hallmarks of heart failure. Agonist occupied βARs undergo desensitization through phosphorylation by G-protein coupled receptor kinases leading to βAR int...
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