Method and apparatus for intra-operative navigation

A method for intra-operative navigation, in which a single receiving a to be examined area of ​​a body (9) and at the same time a single image of a surgical instrument (10) by an optical navigation camera system (1, 2) with a light source (1) and a detector (2 ) can be made, each with three-dimensional information and the images are processed to a three-dimensional position data representation of the to be examined area and the surgical Instuments (10) in a first coordinate system, wherein the position data representation is obtained by optical pulse delay time measurement and Lasertriagulation or optical pulse delay time measurement, and structured illumination, and images of the region to be examined of the body (9) by means of a medical imaging system (11) are made, and are processed to a three-dimensional image data representation of the region to be examined in a second coordinate system, wherein a coordinate transformation between the first coordinate system and the second coordinate system is performed, in which the position data representation and the representation of image data are superimposed and outputted as a combined representation in real time.