Clinical aspects and prognosis of paranasal sinus tumors with special reference to their etiology

: Sixty-one patients operated on for malignant paranasal sinus tumours were investigated to elucidate the incidence and route of metastasis; survival rate, incidence of recurrent tumours, sex distribution etc. as well as possible exogenous causative factors. Adenocarcinomas have a better prognosis in women than in men and sometimes show local recurrences even 10 years and more after primary operation. Tumours of the paranasal sinuses often produce primarily hematogeneous distant metastases, with a fatal outcome. Occupational carcinogenic influence of wood dust seems very likely.