Malignant tumors of the central nervous system associated with familial polyposis of the colon: report of two cases.
1959
Turcot syndrome is the association between familial adenomatous polyposis and brain tumors like medulloblastoma, malignant glioma. It was first reported by Canadian surgeon Jacques Turcot (1914- ) et al in 1959 and hence carries the first author's name.[1]
The genetic basis of Turcot syndrome is uncertain.The gene most likely to be involved is APC gene in chromosome 5q.[2] However, the syndrome has been claimed to be linked to various mutations in a number of genes.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
14
References
399
Citations
NaN
KQI