Guillain-Barré syndrome and variants associated with SARS-CoV-2 infection in Mexico

Background: To date, Mexico has more than 1,280,000 confirmed cases and more than 116,000 deaths due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection Limited information is available regarding Latin American patients with Guillain-Barre syndrome (GBS) and SARS-CoV-2 Objective: The objective is to describe the presentation, diagnosis, and outcome of patients with GBS associated with SARS-CoV-2 infection Methods: We describe four cases of GBS associated with SARS-CoV-2 infection in Mexico Results: Neurological symptoms initiated 2-17 days after the respiratory symptoms The age group in or patients ranged from 26 to 41 years Two patients presented with progressive, acute, and symmetric weakness and two with bilateral facial palsy Patients with GBS diagnosis associated with SARS-CoV-2 infection have been reported to have a good outcome after IGIV or plasma exchange therapy Conclusion: It is important to consider GBS as a potential manifestation of SARS-CoV-2 infection and recall that the diagnosis is based mainly on clinical evaluation Laboratory and CSF analysis, as well as neurophysiologic studies, should be considered as a complement for diagnosis (English) [ABSTRACT FROM AUTHOR] Antecedentes: A la fecha, Mexico tiene mas de 1,280,000 casos confirmados y mas de 116,000 muertes por infeccion por SARS-CoV-2 Se dispone de informacion limitada sobre los pacientes latinoamericanos con sindrome de Guillain-Barre (GBS) y SARS-CoV-2 Objetivo: El objetivo es describir la presentacion, el diagnostico y la evolucion de los pacientes con sindrome de Guillain-Barre asociado a la infeccion por SARS-CoV-2 Metodos: Describimos cuatro casos de SGB asociados a la infeccion por SARS-CoV-2 en Mexico Resultados: Los sintomas neurologicos se iniciaron 2-17 dias despues de los sintomas respiratorios El grupo de edad de los pacientes oscilo entre 26 y 41 anos Dos pacientes presentaron debilidad progresiva, aguda y simetrica y dos con paralisis facial bilateral Se ha reportado que los pacientes con diagnostico de GBS asociado con la infeccion por SARS-CoV-2 tienen un buen resultado despues de la terapia de recambio plasmatico o IGIV Conclusion: Es importante considerar el SGB como una posible manifestacion de la infeccion por SARS-CoV-2 y recordar que el diagnostico se basa principalmente en la evaluacion clinica Los analisis de laboratorio y de LCR, asi como los estudios neurofisiologicos, deben considerarse como un complemento del diagnostico (Spanish) [ABSTRACT FROM AUTHOR] Copyright of Revista Mexicana de Neurociencia is the property of Academia Mexicana de Neurologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission However, users may print, download, or email articles for individual use This abstract may be abridged No warranty is given about the accuracy of the copy Users should refer to the original published version of the material for the full abstract (Copyright applies to all Abstracts )