Reduction in body cell mass as a predictor of osteoporosis: A cross-sectional study

AbstractObjectives: Improvement of nutritional status, which may help prevent osteoporosis, can be assessed using the body cell mass (BCM) index, measured by the bioelectrical impedance method (BIA). However, the relationship between BCM and osteoporosis is not clear. This cross-sectional study investigated the association between osteoporosis and four components of body composition, including BCM.Methods: The study included 600 participants who underwent measurements of bone status by quantitative ultrasound and body composition by BIA at an annual health check-up. Normal and osteoporosis groups were compared.Results: There were 414 and 186 participants in the normal and osteoporosis groups, respectively. Significant differences between the two groups were observed in age, sex, height, weight, BCM, extracellular water content (ECW), and minerals, even after adjusting for age and sex. In logistic regression analysis, BCM, age, and ECW were significant risk factors for osteoporosis. Furthermore, BCM and EC...