Cutaneous infection caused by Curvularia pallescens: A case report and review of the spectrum of disease

Abstract A 75-year-old woman being treated with prednisone and methotrexate had a 5.5 × 2.2 cm ulcer on the leg. A biopsy specimen revealed suppurative, granulomatous dermal inflammation with necrotic areas of septate, branching hyphae containing brown pigment. Cultures grew Curvularia pallescens . Oral ketoconazole therapy was started and the lesion was excised. The site healed after multiple excisions and grafts, and ketoconazole therapy was stopped after 7 months. This is the first reported case of invasive cutaneous infection by C. pallescens .