Synthesis of 2-Triazolyl-imidazo[1,2-a]pyridine Through a One-Pot Three-Component Reaction Using a Nano Copper Oxide Assisted Click-Catalyst.

The synthesis of 2-triazolyl imidazopyridine derivatives (IV) is accomplished by combined coupling reaction followed by 5-exo dig cyclization of triazole carbaldehyde, amidine and terminal alkynes in the presence of nanocopper oxide and sodium ascorbate as a click-catalyst.