A clinical score to predict early death at 100 days after a comprehensive geriatric assessment (CGA) in elderly cancer patients: A prospective study with 815 patients.

9511 Background: Trying to predict very early death after a CGA is very difficult in clinical practice. Last year, we presented predictors of early death (Boulahssass et al, 9511, ASCO 2014).The aim of this new study was the next step by developing a score to estimate the risk of death at 100 days in order to illuminate the clinical decision-making. Methods: This is a multicentric and prospective cohort study approved by an ethics committee. A standardized CGA has been done before the treatment decision at the baseline (MMSE, MNA, Grip strength, ADL, IADL, CIRSg, Charlson, Lee, PS, Gait speed, QLQc30, G8, Balducci score). During the follow up of 100 days, the events (death), the treatments made, and the targeted geriatric interventions were collected. A multivariate logistic regression permits the selection of risk factors. The calibration was assessed with the Hosmer-Lemeshow goodness of fit test. The internal validation of the model was performed by a bootstrap method with 1000 randomized samples. Score...