Coagulation function change in patients with lung cancer

Objective: To observe the coagulation function change in the patients with lung cancer and discuss the relationship of the coagulation function with clinical pathological type and different stages of lung cancer.Methods:We selected 60 patients with lung cancer and 30 healthy subjects.We used an Automatic coagulation analyzer to measure the PT,APTT and Fbg and the synchronous detection of D2 polymer was done.Results:The advanced lung cancer group showed that PT and APTT were significantly reduced(P0.01),and D2 polymer and Fbg were significantly increased(P0.01),with a more obvious increase in advanced small cell lung cancer patients.Conclusion:Most patients with advanced lung cancer show a hypercoagulable state,more obvious in small cell lung cancer.