Pachydermoperiostosis: The Elephant Skin Disease
2017
Pachydermoperiostosis (PDP) was first described in 1868. Three forms have been identified: complete (clubbing, periostosis, pachyderma, and cutis verticis gyrata), incomplete (without cutis verticis gyrata), and forme fruste (pachyderma with minimal skeletal changes)1. Two genes have been associated, HPGD and SLCO2A1 2.
A 27-year-old British Pakistani man presented with clubbing, hyperhidrosis, palmoplantar hyperkeratosis, and painful swollen knees …
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