Analysis of Two Monoclonal Antibodies Defining the Majority and a Subset of Human T Cells

The introduction of hybridoma technology has revolutionised the identification and separation of human T cell subpopulations. In general, specific monoclonal antibodies have been shown to react with either all of the T cells (pan), an inducer subset or a cytotoxic/suppressor subset. In this article we describe the characteristics of two new monoclonal antibodies which react with the majority (MID 5) and a subpopulation of T cells (MID 4).