Investigation and Analysis of Nosocomial Infection in Intensive Care Unit

Objective: To study the changes of flora and bacterial drug resistance of nosocomial infection in intensive care unit (ICU), in order to provide evidence for empirical application of antibiotics and for the control of nosocomial infection. Methods: A retrospective analysis was carried out among 310 isolates in 139 cases during recent 8 years. Results: The most prevalent isolates of pathogens of nosocomial infection were still gram-negative bacilli ( 57.5%), then gram-positive cocci ( 20.6%) and fungi ( 19.7%). In all bacterial organisms, pseudomonas aeruginosa was the major one ( 21.6%). The resistance rate of gram-negative bacteria to imipenem was the lowest. And respiratory tract was the most common site of nosocomial infection. Conclusion: The infected bacteria are mainly G - bacilli. The fungal infection rate was still high with species variation. The changes of bacterial resistance make it diffcult to choose the antibiotics empirically. For avoiding the production of drug resistant bacteria, it is imperative for clinicians should not use drugs blindly.