Synthesis of tritium-labeled cyadox, a promising antimicrobial growth-promoting agent with high specific activity
2018
Abstract Cyadox is a new antimicrobial growth-promoting agent for food-producing animals. Studies on radiolabeled compounds enable the use of sensitive radiometric analytical methods and help in the elucidation of metabolic and elimination pathways. In the present study, 6-[ 3 H]-cyadox with a high specific activity of 2.08 Ci/mmol was prepared by the catalytic bromine–tritium exchange of 4-bromo-2-nitroaniline followed by a three-step microscale synthesis, giving a high yield between 36.16% and 94.75%.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
10
References
0
Citations
NaN
KQI