Impact assessment of bisphenol A on lignin-modifying enzymes by basidiomycete Trametes versicolor

Abstract The impact of different concentrations of bisphenol A (BPA) was evaluated on growth of the white-rot basidiomycete, Trametes versicolor , and on the expression of genes encoding lignin-modifying enzyme (LME) activities. Effective doses (EDs) were obtained from fungal growth rate to monitor LME activities and the expression levels of their encoding genes. The fungus showed mycelial growth at concentrations of up to 300 μg ml −1 of BPA with an ED 50 value of 185 μg ml −1 . The LME activities were stimulated by BPA concentrations up to 300 μg ml −1 . The lignin peroxidase (LIP) encoding gene may be sensitive to BPA stress.