SYNTHESIS OF VERSATILE INTERMEDIATES FOR CYCLOPENTANOID NATURAL PRODUCTS VIA ENANTIOSELECTIVE DEPROTONATION OF SUBSTITUTED CYCLOPENTENE OXIDE

Enantioselective deprotonation of cis and trans-3,4-epoxycyclopentan-1-ol derivatives with phenylglycine based ligand (R)-5 was studied. The cyclopentanoid intermediates were obtained in a maximum of 88% ee.