Epidemiological study on factor VII, factor VIII and fibrinogen in an industrial population: I. Baseline data on the relation to age, gender, body-weight, smoking, alcohol, pill-using, and menopause.

The Munster Arteriosclerosis Study (MAS) is a prospective longitudinal epidemiological study on an industrial population in Westfalia aimed at establishing clinical and laboratory data with a possible connection to cardiovascular events. The data presented here describe the baseline measurements of fibrinogen factor VIIc and factor VIIIc from the recruitment of 2880 males and 1306 females and their relationship to age gender bodyweight smoking alcohol pill use and menopause. The correlations were made by means of a multiple regression analysis. The authors found an increase of those coagulation factors with age a correlation of F VII and fibrinogen with bodyweight index and of fibrinogen with cigarette smoking. No correlation was found for alcohol consumption. F VIII and F VII were significantly higher after onset of menopause and F VII and fibrinogen in women using the pill. (authors)