The effects of strength, aerobic, and concurrent exercise on skeletal muscle damage in rats

Department of Biochemistry, Federal University of Rio Grande do Sul, Porto Alegre, RS, BrazilAccepted 4 October 2013ABSTRACT: Introduction: In this study we examined oxidativestress and skeletal muscle damage resulting from acutestrength, aerobic, or concurrent exercise in rats. Methods: Theanimals were divided into control (C), strength (SE), aerobic(AE), and combined (CE) exercise groups. They were eutha-nized at 3 different time-points (6, 24, and 48 h) after acuteexercise. Results: SE exercise rats had increased dichlorofluor-escein oxidation at 6 h post-exercise and decreased superoxidedismutase activity at all time-points. Glutathione peroxidaseactivity and sulfhydryl levels were increased in the AE group at48 h post-exercise. Serum lactate dehydrogenase activity wasincreased in the SE and CE groups at 24 h and in the AEgroup at 48 h. Echo intensity was elevated at 24 h for allgroups. Conclusions: Forty-eight hours was sufficient for com-plete recovery from oxidative stress and muscle damage in theSE and CE groups, but not in the AE group.