Histopathology and reflectance confocal microscopy features of photodamaged skin and actinic keratosis

BackgroundActinic keratosis (AK) usually co-exists in areas of severe photodamage, but the clinical applicability of reflectance confocal microscopy (RCM) in diagnosing AK currently depends on a set of parameters yet to be defined in comparison to photodamaged skin (PD).