Consolidative radiotherapy in metastatic urothelial cancer (MUC).

406 Background: Although rarely curative, chemotherapy remains the mainstay for the treatment of MUC. In patients with MUC who achieve either partial or complete response to chemotherapy, the role of consolidative radiation remains unknown Methods: From our single institution database of 2597 patients with urothelial carcinoma (UC) treated since 1997, we identified 22 patients with MUC who underwent consolidative radiotherapy after a partial response to chemotherapy with the intent of rendering them disease free. All patients had undergone primary surgical therapy with either cystectomy or nephroureterectomy. We excluded patients who received radiation for a palliative intent. Progression Free survival (PFS) was defined as time from completion of RT to relapse or last follow up. Overall Survival (OS) was defined as time from start of chemotherapy to death or last follow up. Results: The median age of the patients was 67 years; 64% were men and 59% had received prior cisplatin based chemotherapy. The most ...