Function and Mechanism of Nitric Oxide (II) ——— Mechanism and Protein S-Nitrosation

The mechanisms of nitric oxide are complicated,which are involved in the network of multiple targets and need further research.Besides the classic cGMP-dependent signaling pathway,nitric oxide can function through protein post-translational modification on protein cysteine.The formed-SNO is a modification called protein S-nitrosation,which plays important roles in the mechanism of nitric oxide functions.This review briefly summarizes the main function and mechanism of protein S-nitrosation.