Effects of nornicotine enantiomers on intravenous S(−)-nicotine self-administration and cardiovascular function in rats

Dustin J. Stairs,Nichole M. Neugebauer,Xiaochen Wei,Carine M. Boustany,Marhaba Hojahmat,Lisa A. Cassis,Peter A. Crooks,Linda P. Dwoskin,Michael T. Bardo

Effects of nornicotine enantiomers on intravenous S(−)-nicotine self-administration and cardiovascular function in rats

2006

Dustin J. Stairs
Nichole M. Neugebauer
Xiaochen Wei
Carine M. Boustany
Marhaba Hojahmat
Lisa A. Cassis
Peter A. Crooks
Linda P. Dwoskin
Michael T. Bardo

Rationale Previous neurochemical evidence indicates that R(+)-nornicotine is more potent than S(−)-nornicotine in evoking dopamine release in rat nucleus accumbens slices.

Keywords:

Alkaloid
Nornicotine
Neurochemical
Anesthesia
Self-administration
Nicotine
Endocrinology
Nucleus accumbens
Internal medicine
Dopamine
Pharmacology
Medicine
Circulatory system

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