Celecoxib solvent dispersoid, pellet capsule and preparation methods of celecoxib solvent dispersoid and pellet capsule

The invention relates to a celecoxib solvent dispersoid, a pellet capsule and preparation methods of the celecoxib solvent dispersoid and the pellet capsule. The preparation method of the celecoxib solvent dispersoid comprises the following steps: adding a celecoxib raw material and a dispersing and suspending agent into water or ethanol solution, and jointly grinding. The preparation method of the celecoxib solvent dispersoid has the advantages that steps are simple, the problem that condensation and blocking can be easily caused due to strong electrostatic interaction when the celecoxib raw material is used is solved, and the problem that the celecoxib raw material and dispersing matrix are not uniformly mixed is also solved. A preparation method of the celecoxib pellet capsule is characterized in that the celecoxib solvent dispersoid is sprayed onto an outer layer of a core pellet, the aim of removing water or ethanol solution in the solvent dispersoid is achieved while the celecoxib pellet capsule is prepared and loaded with medicine, rebounce of particles can be avoided, and the particles can not be largened. The obtained celecoxib solvent dispersoid is uniformly mixed. The obtained celecoxib pellet capsule is high in solubility and high in dissolution rate.