Recurrent abortion associated with a balanced 22;22 translocation, or isochromosome 22q in a monozygous twin.

A 45,XX,t(22;22)(p11;q11) or 45,XX,i(22q) chromosomal rearrangement was found in a woman with a history of recurrent abortion. A twin sister did not have the translocation even though marker studies indicate that the twins are probably monozygotic.