Interstitial photodynamic therapy for cancers of cavum oris, skin, and cervix

Interstitial photodynamic therapy, in which the straight cut optical fiber was directly inserted into tumors and the insertion points were rationally arranged on an entire lesion area, was performed on 31 oral cancers, 6 skin cancers, and 4 cervix cancers in 41 patients. A highly satisfactory rate of complete response (90%) was obtained via only one treatment. And no severe complication occurred in any of the treatments. The follow-up record for 33 cases with a CR curative effect shows 12 cases have survived free of tumor more than 4 years and only 5 cases relapsed within a year. In this paper, the factors affecting therapeutic effectiveness and the selection of indication are discussed.