A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicity.

Dagmar Fischer,Thorsten Bieber,Youxin Li,Hans Peter Elsässer,Thomas Kissel

A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicity.

1999

Dagmar Fischer
Thorsten Bieber
Youxin Li
Hans Peter Elsässer
Thomas Kissel

Purpose. Low molecular weight branched polyethylenimine (LMW-PEI) was synthesized and studied as a DNA carrier for gene delivery with regard to physico-chemical properties, cytotoxicity, and transfection efficiency.

Keywords:

Gene expression
Polyethylenimine
Biochemistry
DNA
Cytotoxicity
Viral vector
Transfection
Chemistry
Drug carrier
Gene delivery
Molecular biology
genetic transfer

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