Cycle arrest and aneuploidy induced by zidovudine in murine embryonic stem cells

To whom correspondence should be addressed. Laborato´rio Nacional deCe´lulas-Tronco Embriona´rias, Unidade Rio de Janeiro—Laborato´rio Nacionalde ce´lulas-tronco embriona´rias, Hospital Universita´rio Clementino FragaFilho—Laborato´rio Nacional de ce´lulas-tronco embriona´rias, Rua RodolphoPaulo Rocco, 255-4 andar-CEPEDIP, Cidade Universita´ria—Ilha do Funda˜o,Rio de Janeiro RJ 21941-913, Brazil. Tel/Fax: þ55 21 25622931; Email:srehen@lance-ufrj.orgReceived on July 13, 2011; revised on November 22, 2011;accepted on November 24, 2011