Clinical and Psychological Features of Patients with Cerebral Vascular Diseases and Response to Treatment

Aim. To study clinical and paraclinical features in patients with cerebral vascular diseases and their response to treatment. Methods. 121 patients with cerebral vascular diseases (32 males, 89 females, mean age 63.6±8.8 years) were studied before and after the treatment. Patients were divided into groups according to the disease severity. Neurological status, emotional sphere were assessed, other study methods were also used. Results. Neurological symptoms characterizing pyramidal, vestibulo-cerebellar and extrapyramidal syndromes were the most frequent in patients with various cerebral vascular diseases. Symptoms characterizing vestibulo-cerebellar syndrome improved after treatment: dynamic ataxia was present in 66.7% of patients with hypoxic ischemic encephalopathy stage I before treatment compared to 29.2% after treatment, in 44.0% of patients with hypoxic ischemic encephalopathy stage II before treatment compared to 32.0% after treatment, truncal cerebellar ataxia was present in 86.7% of patients before and in 64.0% of patients after treatment and was associated with cognitive potential increase revealed at emotional sphere estimation. The effectiveness of the treatment was confirmed by other study methods. Conclusion. Neurological symptoms including lateral nystagmus, truncal and appendicular ataxia, characterizing vestibulocerebellar syndrome, may be improved after treatment in patients with all groups of cerebral vascular disorders, with the decrease of emotional factor influence and further improvement of the cognitive potential.