Pleomorphic Primitive Neuroectodermal Tumor with Glial and Neuronal Differentiation: Clinical, Pathological, Cultural, and Chromosomal Analysis of a Case
2002
This paper examines a case of pleomorphic primitive neuroectodermal tumor (PNET) with glial and neuronal differentiation in a 7-year-old girl who was clinicopathologically reported with immunohistochemical and chromosomal analysis. Clinically, a highly aggressive behavior leading to early recurrence with cerebrospinal fluid seedings was characteristic despite total removal and chemoradiation therapy. Pathologically, severe pleomorphism was noted and large ganglioid cells were predominant.
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