The Clinical Significance of Serum Transaminase in Infectious Mononucleosis complicated by Hepatitis.

INFECTIOUS mononucleosis is complicated by nonicteric hepatitis in most patients.1 , 2 Confirmation of this generalization is found in a study of patients with infectious mononucleosis during which serial liver biopsies were obtained.3 Although during infectious mononucleosis liver involvement is suggested by liver-function tests, these tests do not actually appear dynamically to reflect the clinical course of the hepatitis. Studies of serum glutamic pyruvic transaminase (SGP-T) and serum glutamic oxaloacetic transaminase (SGO-T) in patients with icteric as well as nonicteric hepatitis indicate that these serum enzymatic parameters are more sensitive reflections of liver injury than the conventionally employed tests of liver function. . . .