A process for preparing a semi-solid preparation containing bispyridiniumalkane

The invention relates to a process for preparing a semi-solid preparation containing bispyridiniumalkane, in which a) is dissolved the bispyridiniumalkane in solvent to prepare a solution of the bispyridinium alkane, and b) the solution of the bispyridinium alkane with one or more further conventional constituents of a semi-solid formulation is mixed. Preferably octenidine dihydrochloride is used as bispyridiniumalkane. Further, the invention according to the method of semi-solid preparations made relates in form of a concentrate in the form of a preparation for use or as a kit. The semi-solid composition is applied in particular to combat MRE to the nasal mucosa, and works equally well as preparations on the basis of mupirocin.