Metformin: Methods of Analysis and Its Role in Lowering the Risk of Cancer

Metformin is the widely used anti-diabetic drug. HPLC is the most widely used method for the analysis of metformin. Others include spectrophotometric and potentiometric methods. The drug is analyzed not only in neat solution but also in pharmaceutical products alone and in combination with other drugs. Studies suggest that metformin can be successfully utilized to reduce the risk of cancer. However, there is a need of a randomized trial to find out if the drug is beneficial among the population at high risk of cancer. This review discusses the different methods utilized for the analysis of metformin and its possible role in resisting the carcinogenesis.