Oxazolidinones and Related Heterocycles as Chiral Auxiliaries/Evans and Post-Evans Auxiliaries

The application of optically active oxazolidinones and their sulfur-incorporating derivatives as chiral auxiliaries for the diastereoselective functionalization of carboxylic acids and related starting materials is described. Herein, seminal work and more recent contributions in this area covering the developments in the past 40 years are summarized. This review aims in demonstrating not only the broad and reliable, synthetic applicability of this auxiliary class but also the methodological impact on the area of diastereoselective chemistry in general.