The Preliminary Evaluation of the Clinical Curative Effect on Carotidatherosclerosis Patients for Shoushen Granules

Objective: To observe the clinical curative effect of compound Chinese medicine for reinforcing kid- ney shoushen granules on carotid atherosclerosis in patients. Methods: 80 patients were randomly divided into two groups. The control group was treated with pravastatin,treatment group took shoushen granules,the treatment course is 6 months. Before and after the treatment with color Doppler ultrasound detection of carotid atherosclero- sis in patients with carotid artery intima-media thickness (IMT),arteriosclerosis detection brachial ankle pulse wave velocity (baPWV) before and after treatment were observed,and the changes of blood lipid in patients with hepatic,renal function and safety index. Results: after 6 months of treatment,the control group IMT,TC,TG, LDL-C and TC/HDL-C ratio were significantly lower than that before treatment,HDL-C significantly increased; baPWV in treatment group was significantly lower than that before treatment,TG,TC/HDL -C were lower than those before therapy,HDL-C significantly increased. Conclusion: Shoushen granules can reduce the IMT,baPWV and improve lipid metabolism and effective intervention for the treatment of carotid atherosclerosis.