Antibiotic susceptibility of strains in Chinese medical probiotic products

Abstract Objective To investigate the susceptibility of strains separated from probiotic products for medical purpose to 14 antimicrobial agents. Methods The single aerobic strains were isolated from these products respectively and disc agar diffusion assay was proceeded to determine the susceptibility. Results Probiotics tested in the study mostly showed multiresistant to the agents. Lactobacillus acidophilus LAP, LAB, Lactobacillus bulgaricus LBJ and Streptococcus thermophilus STJ were resistant to vancomycin. Conclusion Drug resistance exists in most of commercial probiotics. The evaluation and monitoring of safety of probiotic products for medical purpose should be paid great attention.